Scientific Study Shows German-made Homeopathic-Spagyric Topical Ointment Reduces Inflammation
Sunday, September 24, 2017
Posted by: Brook Schales
Submitted by Mike Sheehan with BioResource Inc.
A recent research study conducted by Oregon immunologists confirmed what many users of a popular German-made homeopathic-spagyric topical ointment already knew from firsthand experience: the remedy significantly reduces inflammation while also providing mild antioxidant benefits.
“The purpose of our study was to investigate the ointment’s anti-inflammatory and immune supportive mechanisms of action in bioassays using human cell cultures,” reported immunologist Gitte Jensen, Ph.D., Research Director at NIS Labs in Klamath, Oregon. “We found that this natural remedy triggered biological effects pertaining to immune support, anti-inflammatory effects, and antioxidant protection.”
Developed for the treatment of sports injuries, joint pain, sprains, and muscle strains, the homeopathic-spagyric ointment is manufactured by PEKANA Naturheilmittel GmbH in Germany, and distributed in the U.S. by BioResource Inc. of Cotati, California.
Using human immune and skin cell cultures, the NIS researchers confirmed that the homeopathic-spagyric ointment works in ways that can be substantiated using modern scientific methods. In the presence of inflammation, the ointment had a muting effect and reduced the responses of immune and skin cells to the inflammatory insult. For example, the remedy reduced pro-inflammatory cytokines Interleukin-1-beta and TNF-alpha in the cell cultures by about 50 percent. The study also showed decreases in IL-13, RANTES, IFNg, IL-1b, and IL-10.
Moreover, in the absence of inflammation, application of the ointment supported immune and skin cell activation in manners that suggest effects on immune surveillance and regenerative skin functions.
“The regulation of skin cell cytokine and growth factor production – relevant for immune surveillance, wound healing, and re-epithelialization – is highly interesting for this topical product,” Dr. Jensen pointed out. “I believe it merits further study.”
Overall, the testing examined the effects of the topical ointment on cell viability, cellular protection from oxidative damage, and the formation of reactive oxygen species in human inflammatory cells under oxidative stress conditions. Human immune cell cultures also were applied to evaluate immune activation and cytokine production under both normal and inflammatory culture conditions.
The study resulted in the following conclusions about the homeopathic-spagyric ointment:
- The remedy provides mild cellular antioxidant protection, and contains bioavailable compounds that help protect the inside of the cells from free radical damage.
- When inflammation exists, the remedy reduces immune cell activation and decreases many inflammatory cytokines.
- When there is no inflammation, the remedy activates human immune cells, increases communication between human skin cells and immune cells by triggering signals that suggest increased immune cell trafficking and surveillance.
A hands-on scientist, Dr. Jensen works with an international client base, testing natural products from across the world. She maintains an active profile in the peer-reviewed scientific literature, and continues to take a leading edge with bioassay development, specifically targeted to the study of natural products.